Pterostilbene could potentially treat obesity and type 2 diabetes

The molecule pterostilbene, found in foods and drinks like blueberries and red wine, appears to reduce the build up of body fat. That in turn can reduce the risk of type 2 diabetes and other diseases.

Obesity is traditionally treated by lifestyle changes, including adopting a healthier lifestyle and engaging in more exercise. These strategies, however, do not always have a long-term effectiveness. Including ingredients like pterostilbene in an obese person’s diet may open up greater possibilities for treatment.

While other studies have analysed the effects of pterostilbene, they have focused primarily on cancer. This research is the first to examine the effects of the molecule on obesity in animal models, finding that it reduces body fat by lowering the fat synthesis in adipose tissue, and by increasing its oxidation in the liver.

Future studies will focus on humans rather than animals, with an aim of confirming the obesity-countering effects of the molecule.

The study was conducted by UPV/EHU’s ‘Nutrition and Obesity’ Group in collaboration with the United States Department of Agriculture (USDA). You can find their report here.

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