Boosting NAD+ delays stem cell senescence and reprograms aged somatic cells
Stem cell therapy research is becoming increasingly popular with results to show. In clinical trials, the use of mesenchymal stem cells
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Month: July 2016
Pterostilbene changes gut microbiota, reduces obesity, possibly boosts Urolithin
Over the last 10 to 15 years, the understanding of the composition and functions of the human gut microbiota has increased exponentially.
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Pomegranates, Urolithin A, Mitophagy, Mitochondrial cleanup – (part 1)
Last week a publication in Nature Medicine from the École Polytechnique Fédérale de Lausanne (EPFL) about Urolithin A improving mitochondrial and muscle function led to
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Low dose Nicotinamide Riboside improves metabolic health and anti-oxidant response in mice
Researchers at the Wageningen University in the Netherlands took a different approach to understand the effect of NAD+ pre-cursers and their influence
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Research shows sirtuins regulated by NAD+ concentration, no direct NAD/NADH ratio influence
Sirtuins are NAD-dependent deacetylases that are highly conserved from bacteria to human. SIR2 was originally shown to extend lifespan in
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Study finds boosting SIRT1 may prevent and treat Osteoporosis
Earlier in the year this study linked a decline in mitochondrial function to bone loss and osteoporosis. In this just released
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Why do flavonoid topoisomerase II poisons preferentially kill cancer cells?
Fisetin, quercetin, genistein and some other plant-derived flavonoids have been shown to exhibit antiproliferative effects in several tumor cell lines
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