Dosing: considered to be safe upto 250mg / day

Pterostilbene (trans-3,5-dimethoxy-4-hydroxystilbene) is a natural dietary compound and the primary antioxidant component of blueberries. It has increased bioavailability (meaning it gets easier into the bloodstream) in comparison to other stilbene compounds like resveratrol. This possibly enhance its dietary benefit and possibly contribute to a real clinical effect. Multiple studies have demonstrated the antioxidant activity of pterostilbene in both in vitro and in vivo models illustrating both preventative and therapeutic benefits. Studies also indicate that pterostilbene has anti-inflammatory and anti-cancer activity, lowers cholesterol and improves cognitive function.


Pterostilbene may help to prevent cancer. In-vitro studies demonstrate that pterostilbene induces apoptosis of cancer cells and improves the efficiency of the anti-cancer drug tamoxifen. A study looking at oral efficacy against a highly malignant melanoma tumor showed also limitations wrt its efficacy.

Improves heart health

Studies in test tube and animals show that pterostilbene may improve heart health by lowering cholesterol levels and reducing plaque formation.


Studies indicate the potential use of pterostilbene as an effective anti-inflammatory agent. The phytochemical inhibits the production of prostaglandin E2 from lipopolysaccharides-stimulated human blood cells.

Rejuvenates Brain Cells

The antioxidant and soothing properties of pterostilbene helps brain cell health. Multiple studies have demonstrated pterostilbene supports motor function and cognitive abilities in adults suffering from memory changes.