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Honokiol

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General Nicotinamide Riboside 

End of 2018, that hair is still going strong

December 23, 2018February 10, 2019 Timeless_One 0 Comment anti-aging, Chromadex, curcumin, fisetin, Honokiol, neuroprotection, niagen, nicotinamide riboside, Pterostilbene

My last update is from May this year so I thought I would write a quick note before the year

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General Nicotinamide Riboside 

3 + years use of Niagen (nicotinamide riboside) and plant supplements

May 19, 2018February 10, 2019 Timeless_One 9 Comments anti-aging, Chromadex, curcumin, fisetin, Honokiol, neuroprotection, niagen, nicotinamide riboside, Pterostilbene

Its been a while since I updated the blog. Its because life has been busy and there are so many

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thyroid
Honokiol 

Oral supplementation with honokiol effective against human thyroid cancer in xenograft mouse model

December 24, 2016February 10, 2019 Timeless_One 0 Comment anti-cancer, Honokiol, magnolia, thyroid cancer

In the United States it is estimated that in 2016 approximately 64,000 new patients will be diagnosed with thyroid cancer

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metastasis
Honokiol 

Honokiol shows potential as anti-metastasis drug in lung cancer

September 20, 2016September 20, 2016 Timeless_One 0 Comment cancer, EMT, Honokiol, lung disease, non-small cell lung cancer cells, NSCLC

Honokiol is one of two main biphenolic compounds that are isolated from the bark, seed cones and leaves of Magnolia

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honokiolapoptosis
Honokiol 

Researchers unveil Honokiol brian tumor cell apoptosis and autophagy mechanism in mice

June 6, 2016June 6, 2016 Timeless_One 0 Comment cancer, Glioblastoma multiforme, Honokiol, Malignant glioma, oxidative stress, p53, ROS

Glioblastoma multiforme (GBM) is a fast-growing glioma that develops from star-shaped glial cells that support the health of the nerve

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sirtuinsdepression
Alzheimer's disease depression Nicotinamide Riboside 

Sirtuins and NAD+ linked to depression

April 19, 2016February 10, 2019 Timeless_One 0 Comment depression, fisetin, Honokiol, NAD+, neuroprotection, nicotinamide riboside, SIRTS, sirtuins

Depression is now widely regarded as a common disabling disorder that affects negatively the social functioning of many all over

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Gliomacells
Honokiol 

Honokiol slows malignant brain tumor growth by killing tumor cells in preclinical testing

April 14, 2016April 19, 2016 Timeless_One 1 Comment cancer, Honokiol, Malignant glioma, p53

The symptoms, prognosis, and treatment of a malignant glioma depends on the person’s age, the exact type of tumor and

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Honokiol 

Honokiol a promising insulin sensitizer for the therapy of type 2 diabetes

December 6, 2015December 24, 2016 Timeless_One 0 Comment diabetes, Honokiol

In an in vivo study in diabetes mellitus mice, oral treatment with 200 mg/kg honokiol for 8 weeks significantly decreased

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renal cells
Honokiol 

In vitro study shows that Honokiol suppresses metastasis of aggressive renal cell cancer

June 28, 2015April 11, 2016 Timeless_One 0 Comment cancer, Honokiol, renal cells

Renal cell cancer (also called kidney cancer or renal adenocarcinoma) is a disease in which malignant (cancer) cells are found

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Honokiol
Honokiol 

Honokiol combats head and neck cancers in lab

June 20, 2015April 8, 2016 Timeless_One 0 Comment cancer, EGFR, Honokiol

This study is done with human cell line xenografts in athymic nude mice. The so called Xenotransplantation is the transplantation

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Compounds & Supplements

  • Nicotinamide Riboside
  • Pterostilbene
  • Honokiol
  • Quercetin
  • Fisetin
  • Anthocyanins

Popular posts & pages

  • Personal experiences: My hair regrowth and why I think an NR experiment may
  • Personal Experiences (updated 26th of March 17)
  • Nicotinamde Riboside Dosing Overview (updated 11th of November 2016)
  • Study shows mice on NMN drinking water stay young, makes questionable…
  • Star research team maps NR and NMN conversion path to cellular NAD+
  • SIRT1 boosting with nutraceuticals, study reveals most effective compounds…
  • Nicotinamide Riboside
  • 3 + years use of Niagen (nicotinamide riboside) and plant supplements
  • New safety assessment of nicotinamide riboside published
  • Longevity news and studies

Health challenges

  • Alzheimer's disease
  • Advanced Glycation End products
  • Obesity

Miscellaneous articles

  • End of  2018, that hair is still going strong

    End of 2018, that hair is still going strong

    December 23, 2018
  • 3 + years use of Niagen (nicotinamide riboside) and plant supplements

    3 + years use of Niagen (nicotinamide riboside) and plant supplements

    May 19, 2018
  • Personal experiences: dosing & timing experiment

    Personal experiences: dosing & timing experiment

    November 25, 2017
  • Niagen sales grow on Amazon.com to 7.9M USD/Year (September estimation) + Best sellers & Best prices.

    Niagen sales grow on Amazon.com to 7.9M USD/Year (September estimation) + Best sellers & Best prices.

    October 1, 2017
  • Niagen sales on Amazon.com: 5.6M USD/Year (estimation). List of best sellers & best prices.

    Niagen sales on Amazon.com: 5.6M USD/Year (estimation). List of best sellers & best prices.

    July 29, 2017
  • Personal experiences: Summer is here

    Personal experiences: Summer is here

    July 18, 2017
  • Richest man in Asia invests in Chromadex (Niagen), will own 20% of company

    Richest man in Asia invests in Chromadex (Niagen), will own 20% of company

    April 28, 2017
  • Personal experiences: became 47 this week, 2 years of nutraceuticals, can I stay in my 30s forever?

    Personal experiences: became 47 this week, 2 years of nutraceuticals, can I stay in my 30s forever?

    March 26, 2017
  • Elysium Health appears  under increasing criticism, now sued for not paying bills

    Elysium Health appears under increasing criticism, now sued for not paying bills

    January 8, 2017
  • Personal experiences: My hair regrowth and why I think an NR experiment may be the reason

    Personal experiences: My hair regrowth and why I think an NR experiment may be the reason

    November 22, 2016
  • Study shows mice on NMN drinking water stay young, makes questionable dosing conclusion

    Study shows mice on NMN drinking water stay young, makes questionable dosing conclusion

    November 5, 2016
  • SIRT1 boosting with nutraceuticals, study reveals most effective compounds and combinations

    SIRT1 boosting with nutraceuticals, study reveals most effective compounds and combinations

    October 21, 2016
  • More proof coffee may make you old, inhibits SIRT1,2 & 3

    More proof coffee may make you old, inhibits SIRT1,2 & 3

    October 15, 2016
  • personal experiences update – facial structure picture comparison after 1.5 year use

    personal experiences update – facial structure picture comparison after 1.5 year use

    September 18, 2016
  • Pomegranates, Urolithin A, Mitophagy, Mitochondrial cleanup –  (part 1)

    Pomegranates, Urolithin A, Mitophagy, Mitochondrial cleanup – (part 1)

    July 20, 2016
  • Research shows sirtuins regulated by NAD+ concentration, no direct NAD/NADH ratio influence

    Research shows sirtuins regulated by NAD+ concentration, no direct NAD/NADH ratio influence

    July 9, 2016
  • Why do flavonoid topoisomerase II poisons preferentially kill cancer cells?

    Why do flavonoid topoisomerase II poisons preferentially kill cancer cells?

    July 5, 2016
  • Man with severe dementia significantly recovers after treatment with natural enzyme

    Man with severe dementia significantly recovers after treatment with natural enzyme

    June 10, 2016
  • Study provides evidence that supplements may help prevent cancer in your dog

    Study provides evidence that supplements may help prevent cancer in your dog

    May 30, 2016
  • Dark chocolate is neuroprotective in rats prone to Alzheimer’s Disease

    Dark chocolate is neuroprotective in rats prone to Alzheimer’s Disease

    May 4, 2016
  • Coffee makes you old? Study indicates that coffee extract inhibits SIRT1/2

    Coffee makes you old? Study indicates that coffee extract inhibits SIRT1/2

    April 6, 2016
  • The epigenetic role of vitamin C in health and disease

    The epigenetic role of vitamin C in health and disease

    April 5, 2016
  • This is how men look at the age of 46 and 40

    This is how men look at the age of 46 and 40

    April 2, 2016
  • 37.2 trillion cells and other incredible cell statistics about the human body

    37.2 trillion cells and other incredible cell statistics about the human body

    March 29, 2016
  • Most popular Amino Acids – search statistics

    Most popular Amino Acids – search statistics

    March 24, 2016
  • Impressive success in regeneration of eye lenses with stem cells

    Impressive success in regeneration of eye lenses with stem cells

    March 10, 2016
  • Fine-Tuning and regulation of Cellular Energy Increases Longevity

    Fine-Tuning and regulation of Cellular Energy Increases Longevity

    March 8, 2016
  • Short-lived killifish reveals connection between gene expression and longevity

    Short-lived killifish reveals connection between gene expression and longevity

    March 7, 2016
  • Mitochondrial energy decline cause for failing hearts

    Mitochondrial energy decline cause for failing hearts

    February 28, 2016
  • Scientists find decline in mitochondrial Complex II activity in senescent human skin cells as we age

    Scientists find decline in mitochondrial Complex II activity in senescent human skin cells as we age

    February 20, 2016
  • Scientists have identified 1500 genes connected to how we age

    Scientists have identified 1500 genes connected to how we age

    October 25, 2015
  • Parkinson’s patients ‘walk and talk again’ when taking cancer drug

    Parkinson’s patients ‘walk and talk again’ when taking cancer drug

    October 19, 2015
  • Antioxidants linked to spread of skincancer

    Antioxidants linked to spread of skincancer

    October 17, 2015
  • Why elephants rarely get cancer: Potential mechanism identified that may be key to cancer resistance

    Why elephants rarely get cancer: Potential mechanism identified that may be key to cancer resistance

    October 12, 2015

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