Boosting NAD+ delays stem cell senescence and reprograms aged somatic cells
Stem cell therapy research is becoming increasingly popular with results to show. In clinical trials, the use of mesenchymal stem cells
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mitochondria
Pomegranates, Urolithin A, Mitophagy, Mitochondrial cleanup – (part 1)
Last week a publication in Nature Medicine from the École Polytechnique Fédérale de Lausanne (EPFL) about Urolithin A improving mitochondrial and muscle function led to
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Quercetin & Apegenin slow down the escalating NAD+ consumption by CD38 as we age
The last months have seen a couple publications highlighting a link between the expression and activity of the NADase CD38
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Protecting mitochondrial function is linked to improved bone health in aging and resistance to osteoporosis
Reduced bone mass and mineral density are common characteristics in aging bone, leading to a significant increase of fracture risk
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NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice
Significant new findings about the effects of boosting NAD+ with nicotinamide riboside were published yesterday in Science. The researchers demonstrated
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Short-lived killifish reveals connection between gene expression and longevity
A study that appeared in the February 24 edition of Cell Systems indicates that differences in patterns of gene expression
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Mitochondrial energy decline cause for failing hearts
The laboratory of Daniel Kelly, at SBP’s Lake Nona campus, published research showing that muscle cells in failing hearts contain
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Scientists find decline in mitochondrial Complex II activity in senescent human skin cells as we age
For the first time, scientists at Newcastle University have identified that the activity of a specific and key metabolic enzyme found in
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Honokiol increases SIRT3 levels and stops cardiac hypertrophy in mice
In an expansive study, researchers found that Honokiol increases levels of SIRT3. This appears to be the first ever report
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Nicotinamide Riboside induces mitochondrial biogenesis in myopathy mice
Nutrient availability is the major regulator of life and reproduction, and a complex cellular signaling network has evolved to adapt
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