Study shows mice on NMN drinking water stay young, makes questionable dosing conclusion
A team largely comprised out of researchers from the Washington University School of Medicine conducted a 12-month-long experiment in which
Read more
NAD+
Star research team maps NR and NMN conversion path to cellular NAD+
An in-depth paper was released in Nature Communications this month with an impressive line up of researchers incl. Charles Brenner
Read more
200 page research work behind several Nicotinamide Ribose PRs published online
This week the thesis work behind for example the press releases “Nicotinamide Riboside increases the Co-enzyme NAD+ in Human Clinical
Read more
Boosting NAD+ delays stem cell senescence and reprograms aged somatic cells
Stem cell therapy research is becoming increasingly popular with results to show. In clinical trials, the use of mesenchymal stem cells
Read more
Research shows sirtuins regulated by NAD+ concentration, no direct NAD/NADH ratio influence
Sirtuins are NAD-dependent deacetylases that are highly conserved from bacteria to human. SIR2 was originally shown to extend lifespan in
Read more
Study finds boosting SIRT1 may prevent and treat Osteoporosis
Earlier in the year this study linked a decline in mitochondrial function to bone loss and osteoporosis. In this just released
Read more
Quercetin & Apegenin slow down the escalating NAD+ consumption by CD38 as we age
The last months have seen a couple publications highlighting a link between the expression and activity of the NADase CD38
Read more
Protecting mitochondrial function is linked to improved bone health in aging and resistance to osteoporosis
Reduced bone mass and mineral density are common characteristics in aging bone, leading to a significant increase of fracture risk
Read more
Nicotinamide Riboside supplementation may reverse aging related symptoms of liver disease (NAFLD)
Increasing evidence about the importance NAD+ levels in the body continuous to emerge. This week reseachers in China released a
Read more
Alcohol may injure the liver, other organs by reducing NAD+ pool required for sirtuin activity
Using existing research and experimental results a scientist pieces a mechanism together how alcohol injures the liver and other organs
Read more